Monday, May 2, 2005

Innovation Book Available for Free Download

Democratizing Innovation, a new book by Eric von Hippel, is available for free download in PDF format via a Creative Commons license. The book can be downloaded in a single file or by chapter.

Von Hippel heads the Innovations and Enterpreneurship Group at the MIT Sloan School of Management. Among the key themes of the book is that innovative organizations must work directly with "lead users," customers who are prone to customizing and hacking their products. In this way, organizations can learn what their customers really want rather than merely assuming and guessing what they want.

One caveat: Democratizing Innovation is dense, academic reading. However, it's not a long book, so if you're accustomed to this style of writing, you can polish it off in short order.

Source: Innovation Weblog

Fighting Cancer with Smart "Nanocarriers"

The big problem with many cancer treatments -- namely chemotherapy -- is that they take a "scorched earth" approach by attacking healthy as well as cancerous cells. Hence, the fatigue, nausea, hair loss and other unpleasant side effects. And hence, the drive toward developing more precise forms of cancer treatment.

One promising approach being pioneered by Singapore's Institute of Bioengineering and Nanotechnology (IBN) is the use of "nanocarriers" -- tiny capsules (200 nanometers) designed to react with specific cancer tissues. The nanocarriers are pH-sensitive, so they react with, and only with, tumors that exhibit a specific pH balance. As a result, they don't release their medicine payload until they reach the appropriate point in the body, thereby sparing healthy cells. So far, the IBN team has demonstrated the effectiveness of the nanoparticles with cancerous tumors in mice.

The clear benefit of nanoparticles is to make cancer treatments more effective, more rapid and less traumatic to the patient. And, because it would presumably reduce waste and risk, nanocarriers could also lower costs.

Source: PhysOrg

 
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